Clinical Biochemistry: An Illustrated Colour Text (6th Edition)

Description

This comprehensively revised edition of Clinical Biochemistry offers essential reading for today’s students of medicine and other health science disciplines – indeed, anyone who requires a concise, practical introduction to the subject. Topics are clearly presented in a series of double-page ‘learning units’, each covering a particular aspect of clinical biochemistry. Four sections provide a core grounding in the subject:

• Introducing clinical biochemistry gives an insight into how modern hospital laboratories work, and includes an entirely new series of learning units on the interpretation of test results
• Core biochemistry covers the bulk of routine analyses, and their relevance to the clinical setting
• Endocrinology provides an overview of endocrine investigations as well as a practical approach to thyroid, adrenal, pituitary and gonadal function testing
• Specialised investigations embraces an assortment of other topics that students may encounter

This edition represents the most radical revision of the book to date. Every learning unit has been examined and updated to reflect current developments and clinical best practice. Entirely new material includes a series of learning units on interpretation and analytical aspects of clinical biochemistry. Coverage of fluid biochemistry is now more comprehensive. New “Want to know more?” links throughout the book point readers to relevant further information.

• (Printed version) now includes the complete eBook version for the first time – downloadable for anytime access and enhanced with new, interactive multiple choice questions for each section, to test your understanding and aid exam preparation

Table of Contents

1. Part 1: Introducing clinical biochemistry
   1. The clinical biochemistry laboratory
   2. The use of the laboratory
   3. Interpretation of results: general
   4. Interpretation of results: diagnosis
   5. Interpretation of results: monitoring
   6. Analytical aspects
2. Part 2: Core biochemistry
   1. Fluid and electrolytes: basic concepts
   2. Water and sodium balance: physiological mechanisms
   3. Hyponatraemia: pathophysiology
   4. Hyponatraemia: assessment and management
   5. Hypernatraemia
   6. Hyperkalaemia
   7. Hypokalaemia
   8. Intravenous fluid therapy
   9. Investigation of renal function (1)
   10. Investigation of renal function (2)
   11. Urinalysis
   12. Proteinuria
   13. Acute kidney injury
   14. Chronic kidney disease
   15. Acid–base: concepts and vocabulary
   16. Metabolic acid–base disorders
   17. Respiratory and mixed acid–base disorders
   18. Acid–base disorders: diagnosis and management
   19. Proteins and enzymes
   20. Immunoglobulins
   21. Myocardial infarction
   22. Liver function tests
   23. Jaundice
   24. Liver disease
   25. Glucose metabolism and diabetes mellitus
   26. Diagnosis and monitoring of diabetes mellitus
   27. Diabetic ketoacidosis
   28. Hypoglycaemia
   29. Calcium regulation and hypocalcaemia
   30. Hypercalcaemia
   31. Phosphate and magnesium
   32. Metabolic bone disease
   33. Osteoporosis and fragility fractures
3. Part 3: Endocrinology
   1. Endocrine control
   2. Dynamic function tests
   3. Pituitary function
   4. Growth disorders and acromegaly
   5. Thyroid pathophysiology
   6. Hypothyroidism
   7. Hyperthyroidism
   8. Adrenocortical pathophysiology
   9. Hypofunction of the adrenal cortex
   10. Hyperfunction of the adrenal cortex
   11. Gonadal function
   12. Subfertility
4. Part 4: Specialized investigations
   1. Nutritional assessment
   2. Nutritional support
   3. Parenteral nutrition
   4. The metabolic response to injury
   5. Gastrointestinal disorders
   6. Iron
   7. Zinc and copper
   8. Therapeutic drug monitoring
   9. Toxicology
   10. Metal poisoning
   11. Alcohol
   12. Ascites
   13. Pleural fluid
   14. Cerebrospinal fluid
   15. Identification of body fluids
   16. Lipoprotein metabolism
   17. Clinical disorders of lipid metabolism
   18. Hypertension
   19. Cancer and its consequences
   20. Tumour markers
   21. Multiple endocrine neoplasia
   22. Hyperuricaemia
   23. Myopathy
   24. Fetal monitoring and prenatal diagnosis
   25. Pregnancy
   26. Antenatal screening
   27. Screening the newborn for disease
   28. Paediatric biochemistry
   29. Inborn errors of metabolism
   30. Selected inherited disorders
5. Case history comments
6. Online self-assessment
7. Index

Author Biography

Michael J. Murphy, MA MD FRCP FRCPath, Clinical Reader in Biochemical Medicine, University of Dundee, Dundee, UK,

Rajeev Srivastava, MS FRCS FRCPath, Consultant Clinical Biochemist, NHS Greater Glasgow & Clyde, Glasgow, UK

Kevin Deans, PhD FRCP FRCPath, Consultant Clinical Biochemist, NHS Grampian, Aberdeen, UK