Kelley and Firestein’s Textbook of Rheumatology 2 Volume Set (10th Edition) | KitaabNow

Kelley and Firestein’s Textbook of Rheumatology 2 Volume Set (10th Edition)

  • Authors: Gary S. Firestein, Ralph C. Budd, Sherine E Gabriel, Iain B McInnes, James R O’Dell
  • ISBN: 9780323316965
  • Publisher: Elsevier Science Publishing
  • Edition: 10th
  • Publication Date: June 21, 2016
  • Format: Hardback – 2288 pages
  • Language: English


Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein Ralph C. Budd Sherine E. Gabriel Iain B. McInnes and James R. O’Dell and authored by internationally renowned scientists and clinicians in the field Kelley and Firestein’s Textbook of Rheumatology 10th Edition delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science immunology anatomy and physiology to diagnostic tests procedures and specific disease processes this state-of-the-art reference provides a global authoritative perspective on the manifestations diagnosis and treatment of rheumatic diseases.

New to this Edition
  • New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases.
  • New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies.
  • More schematic diagrams clearly summarize information and facilitate understanding.
Key Features
  • An ideal balance of the basic science you need to know and how to apply that information to clinical practice.
  • An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes.
  • Videos online demonstrate the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints.
Table of Contents
  1. Biology of the Normal Joint
  2. Synovium
  3. Cartilage and Chondrocytes
  4. Biology, Physiology, and Morphology of Bone
  5. Muscle: Anatomy, Physiology, and Biochemistry
  6. Biomechanics
  7. Tissue Engineering
  8. Proteinases and Matrix Degradation
  9. Dendritic Cells
  11. Neutrophils
  12. T Lymphocytes
  13. B Cells
  14. Fibroblasts and Fibroblast-like Synoviocytes
  15. Mast Cells
  16. Platelets and Rheumatic Diseases
  17. Innate Immunity
  18. ADAPTIVE IMMUNITY and Organization of Lymphoid Tissues
  19. Autoimmunity
  21. Genetics of Rheumatic Diseases
  22. Epigenetics of rheumatic diseases
  23. Complement System
  24. Prostaglandins, Leukotrienes, and Related Compounds
  25. Cell Recruitment and Angiogenesis
  26. Cytokines
  28. Cell Survival and Death in Rheumatic Diseases
  29. Animal Models of Rheumatic Diseases
  30. Neural regulation of Pain and Inflammation
  33. Assessment of Health Outcomes IN RHEUMATIC DISEASES
  34. Biologic Markers
  35. Occupational and Recreational MSK Disorders
  36. Cardiovascular Risk in Rheumatic Disease
  37. Cancer Risk in Rheumatic Diseases
  38. Introduction to Physical Medicine, Physical Therapy and Rehabilitation
  39. Pregnancy and Rheumatic Diseases
  40. History and Physical Examination of the Musculoskeletal System
  43. The Skin and Rheumatic Diseases
  44. The Eye and Rheumatic Diseases
  45. Neck Pain
  46. Shoulder Pain
  47. Low Back Pain
  48. Hip and Knee Pain
  49. Ankle and Foot Pain
  50. Hand and Wrist Pain
  51. Temporomandibular Joint Pain
  52. Fibromyalgia
  53. Synovial Fluid Analysis, Synovial Biopsy, and Synovial Pathology
  54. Arthrocentesis and Injection of Joints and Soft Tissue
  55. Antinuclear Antibodies
  56. Autoantibodies in rheumatoid arthritis
  57. Acute Phase Reactants
  58. Imaging Modalities in Rheumatic Disease
  59. Prostanoid Biology and its Therapeutic Targeting
  60. Glucocorticoid Therapy
  61. Traditional DMARDS: Methotrexate, Leflunomide, Sulfasalazine, and Hydroxychloroquine and Combination Therapies
  62. TRADITIONAL Immunoregulatory Drugs
  63. Anticytokine Therapies
  64. Cell Targeted Biologics
  66. Urate Lowering Therapy
  67. Analgesic Agents in Rheumatic Diseases
  68. Nutrition and Rheumatic Disease
  69. Etiology and Pathogenesis of Rheumatoid Arthritis
  70. Clinical Features of Rheumatoid Arthriti
  71. Treatment of Rheumatoid Arthritis
  72. Early Synovitis and Early Undifferentiated Arthritis
  73. Sjogren’s Syndrome
  74. Etiology and Pathogenesis of Spondyloarthropathies
  75. Ankylosing Spondylitis
  76. Undifferentiated Spondyloarthritis and Reactive Arthritis
  77. Psoriatic Arthritis
  78. Enteropathic Arthritis
  79. Etiology and Pathogenesis of SLE
  80. Clinical Features of SLE
  81. Treatment of SLE
  82. Antiphospholipid Syndrome
  83. Etiology and Pathogenesis of Scleroderma
  84. Clinical Features and Treatment of Scleroderma
  85. Inflammatory Diseases of Muscle and Other Myopathies
  86. Overlap Syndromes
  87. Classification and Epidemiology of Systemic Vasculitis
  88. Giant Cell Arteritis, Polymyalgia Rheumatica, and Takayasu’s Arteritis
  89. Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
  90. Polyarteritis and Related Disorders
  91. Immune Complex-Mediated Small Vessel Vasculitis
  92. Isolated Angiitis of the Nervous System
  93. Bechet’s Disease
  94. Etiology and Pathogenesis of Gout and Hyperuricemia
  95. Clinical Features and Treatment of Gout
  96. Calcium Crystal Diseases: Calcium Pyrophosphate Dihydrate and Basic Calcium Phosphate
  97. Familial Autoinflammatory Syndromes
  98. Etiology and Pathogenesis of Osteoarthritis
  99. Clinical Features of Osteoarthritis
  100. Treatment of Osteoarthritis
  101. Metabolic Bone Disease
  102. Proliferative Bone Disease
  103. Osteonecrosis
  104. Relapsing Polychondritis
  105. Heritable Diseases of Connective Tissue
  106. Etiology and Pathogenesis of Juvenile Idiopathic Arthritis
  107. Treatment of Juvenile Inflammatory Arthritis
  108. SLE, Juvenile Dermatomyositis, Scleroderma and Vasculitis
  109. Bacterial Arthritis
  110. Lyme Disease
  111. Mycobacterial Infections of Bones and Joints
  112. Fungal Infections of Bones and Joints
  113. Rheumatic Manifestations of HIV Infection
  114. Viral Arthritis
  115. Rheumatic Fever and Post-Streptococcal Arthritis
  116. Amyloidosis
  117. Sarcoidosis
  118. Hemachromotosis
  119. Hemophilic Arthropathy
  120. Rheumatic Manifestations of Hemoglobinopathies
  122. Arthritis Accompanying Endocrine and Metabolic Disorders
  123. Musculoskeletal Syndromes Associated with Malignancy
  124. Tumors and Tumor-like Lesions of Joints and Related Structures
Authors Biography

Gary S. Firestein, MD, Distinguished Professor of Medicine, Dean and Associate Vice Chancellor of Translational Medicine, University of California San Diego School of Medicine, La Jolla, California

Ralph C. Budd, MD, Professor of Medicine and Microbiology and Molecular Genetics, Director, Vermont Center for Immunology and Infectious Diseases, University of Vermont College of Medicine Distinguished University Professor, The University of Vermont College of Medicine, Burlington, Vermont

Sherine E Gabriel, MD, MSc, Professor and Dean, Rutgers Robert Wood Johnson Medical School, CEO, Robert Wood Johnson Medical Group, Emeritus Professor, Mayo Clinic, New Brunswick, New Jersey

Iain B McInnes, PhD, FRCP, FRSE, FMedSci, Muirhead Professor of Medicine, Arthritis Research UK Professor of Rheumatology, Director of Institute of Infection, Immunity, and Inflammation , College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom

James R O’Dell, MD, Bruce Professor and Vice Chairman of Internal Medicine, University of Nebraska Medical Center, Chief of Rheumatology, Department of Medicine, Omaha Veterans Affairs, Omaha, Nebraska

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