Neurology Evidence: The Practice-Changing Studies | KitaabNow

Neurology Evidence: The Practice-Changing Studies

  • Edited By: Emily L. Aaronson, Dr. Erik L. Antonsen, Arjun K. Venkatesh, Kate T. Brizzi, Ayush Batra, Joel Salinas, Nancy Wang
  • ISBN: 9781496348937
  • Publisher: Wolters Kluwer Publishing
  • Edition: 1st
  • Publication Date: September 5, 2017
  • Format: Paperback – 252 Pages
  • Language: English


Synthesizing the vast body of literature available in neurology into one accessible, clinically relevant volume, Neurology Evidence: The Practice-Changing Studies is an invaluable resource for students, residents, and fellows, as well as neurologists at all levels of experience. Featuring the top 100 papers that have had the most significant impact on changing clinical practice, this unique title analyzes the strengths and weaknesses of both seminal and less-noticed studies. Readable commentary is provided for each study by both a senior and junior neurologist in each subspecialty.

Key Features
  • Focuses on those studies that have had the greatest impact on how neurologists care for patients today, explaining the relevance of the information, engaging readers through questions and answers, and offering commentary on future directions.
  • Analyzes the insights gained from both positive and negative trials, with the overall goal of improving clinical outcomes for patients suffering from neurological disease.
  • Provides interpretation by residents and fellows with a particular interest in each clinical topic, as well as the input of accomplished senior neurologists.
  • Includes multiple studies on ischemic stroke, cerebral hemorrhage, traumatic brain injury, neurologic intensive care, neuroinfectious diseases, neuro-oncology, neuromuscular diseases, movement disorders, multiple sclerosis, autoimmune neurology, epilepsy, headache and pain, cognitive neurology, and pediatric neurology.

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Table of Contents
  1. Section 1: Ischemic Stroke
  2. Authors: Mark Etherton, Jesse Thon
  3. Senior Author: Steven K. Feske
    1. Chapter 1: Intravenous tPA for acute ischemic stroke
    2. Chapter 2: Aspirin for secondary stroke prevention
    3. Chapter 3: Mechanical thrombectomy for large vessel occlusion
    4. Chapter 4: Harm from stenting of symptomatic intracranial arterial stenoses
    5. Chapter 5: Warfarin for atrial fibrillation
    6. Chapter 6: Novel oral anticoagulants for stroke prevention in non-valvular atrial fibrillation
    7. Chapter 7: Intense low-density lipoprotein cholesterol reduction for stroke prevention
    8. Chapter 8: Marginal benefit from device closure of patent foramen ovale
    9. Chapter 9: Early decompressive surgery in malignant infarction of the middle cerebral artery
    10. Chapter 10: Carotid endarterectomy for stroke prevention in internal carotid artery stenosis
    11. Chapter 11: Carotid artery stenting versus carotid endarterectomy for symptomatic and asymptomatic carotid artery stenosis
    12. Chapter 12: Warfarin and aspirin in patients with heart failure and sinus rhythm
    13. Chapter 13: Short-term dual antiplatelet therapy for stroke prevention after TIA or minor stroke
    14. Chapter 14: Aspirin over warfarin for symptomatic intracranial stenosis
    15. Chapter 15: Lack of benefit from long-term dual antiplatelet therapy for secondary stroke prevention
    16. Chapter 16: Fluoxetine for motor recovery after acute ischemic stroke
    17. Chapter 17: Carotid endarterectomy for asymptomatic carotid artery stenosis
    18. Chapter 18: Extended monitoring for paroxysmal atrial fibrillation
    19. Chapter 19: The National Institutes of Health Stroke Scale
  4. Section 2: Cerebral Hemorrhage
  5. Authors: David J. Lin, Saad Mir
  6. Senior Author: Stephen M. Greenberg
    1. Chapter 20: Blood pressure regulation in parenchymal intracerebral hemorrhage
    2. Chapter 21: Early surgery for spontaneous intracerebral hemorrhage and hydrocephalus
    3. Chapter 22: Avoidance of long-term anticoagulation for atrial fibrillation after intracerebral hemorrhage
    4. Chapter 23: Nimodipine for prevention of delayed neurologic injury after subarachnoid hemorrhage
    5. Chapter 24: Inferiority of surgical resection to medical management of unruptured AVM
    6. Chapter 25: Prognostication for intracerebral hemorrhage
    7. Chapter 26: Acute endovascular treatment for ruptured subarachnoid hemorrhage
    8. Chapter 27: Neurosurgical clipping versus endovascular coiling of ruptured intracranial aneurysms
    9. Chapter 28: Withdrawal of support in intracerebral hemorrhage due to predicted poor prognosis may lead to self-fulfilling prophecy
    10. Chapter 29: rTPA for intraventricular hemorrhage
    11. Chapter 30: Grading of ruptured subarachnoid hemorrhages
  7. Section 3: Traumatic Brain Injury
  8. Author: Daniel B. Rubin
  9. Senior Author: Brian L. Edlow
    1. Chapter 31: Glasgow Coma Scale
    2. Chapter 32: Albumin versus saline for resuscitation after traumatic brain injury
    3. Chapter 33: Decompressive craniectomy in traumatic brain injury
    4. Chapter 34: Antiepileptic drugs after traumatic brain injury
    5. Chapter 35: Intracranial pressure monitoring in traumatic brain injury
    6. Chapter 36: Amantadine for recovery of consciousness after traumatic brain injury
    7. Chapter 37: Functional imaging in vegetative states
    8. Chapter 38: Corticosteroids for traumatic brain injury
    9. Chapter 39: Corticosteroids in acute spinal cord injury
  10. Section 4: Neurologic Intensive Care
  11. Authors: David J. Lin
  12. Senior Author: Henrikas Vaitkevicius
    1. Chapter 40: Midline shift and level of consciousness
    2. Chapter 41: Hyperosmolar therapy for intracranial pressure
    3. Chapter 42: Hyperventilation for acute intracranial elevation
    4. Chapter 43: Temperature management for cardiac arrest in adults
    5. Chapter 44: Early mobilization in the intensive care unit
  13. Section 5: Neuroinfectious Diseases
  14. Author: Altaf Saadi
  15. Senior Author:Jennifer Lyons
    1. Chapter 45: Glucocorticoids for bacterial meningitis in adults
    2. Chapter 46: Acyclovir for Herpes Simplex encephalitis
    3. Chapter 47: Polymerase chain reaction testing for Herpes Simplex Encephalitis
    4. Chapter 48: Antifungal therapy for Cryptococcal meningitis
    5. Chapter 49: Guidelines for treatment of Lyme disease in the nervous system
  16. Section 6: Neuro-oncology
  17. Author: Maya Graham
  18. Senior Author: Mikael Rinne
    1. Chapter 50: Temozolomide for glioblastoma
    2. Chapter 51: Surgery for brain metastases
    3. Chapter 52: Chemotherapy for low-grade glioma
    4. Chapter 53: NovoTTF for newly-diagnosed glioblastoma
    5. Chapter 54: Bevacizumab for recurrent glioblastoma
    6. Chapter 55: Methotrexate for primary CNS lymphoma
  19. Section 7: Neuromuscular
  20. Author: Kathleen McKee
  21. Senior Author: Michael Bowley
    1. Chapter 56: Acute treatment for Guillain-Barre syndrome
    2. Chapter 57: Alternate day prednisone in myasthenia gravis
    3. Chapter 58: IVIg vs. prednisone for chronic inflammatory demyelinating polyneuropathy
    4. Chapter 59: Glucocorticoid steroids for Duchenne muscular dystrophy
    5. Chapter 60: Riluzole in amyotrophic lateral sclerosis
    6. Chapter 61: Thymectomy in myasthenia gravis
  22. Section 8: Movement Disorders
  23. Author: Abby Olsen
  24. Senior Author: Todd Herrington
    1. Chapter 62: L-dopa for Parkinson’s disease
    2. Chapter 63: Deep brain stimulation for Parkinson’s disease
    3. Chapter 64: Deep brain stimulation for dystonia
    4. Chapter 65: L-dopa vs MAO-B inhibitors in Parkinson’s disease
    5. Chapter 66: Propranolol treatment for essential tremor
    6. Chapter 67: Rasagaline in Parkinson’s disease
    7. Chapter 68: Botulin A toxin for dystonia
  25. Section 9: Multiple Sclerosis
  26. Author: Tamara Kaplan
  27. Senior Author: James Stankiewicz
    1. Chapter 69: Progressive multifocal leukoencephalopathy after treatment with natalizumab
    2. Chapter 70: Glucocorticoids for optic neuritis: the optic neuritis treatment trial
    3. Chapter 71: NMO antibody in the diagnosis of neuromyelitis optica
    4. Chapter 72: Correlation between MRI findings and disability in multiple sclerosis
    5. Chapter 73: The association of Vitamin D levels and multiple sclerosis
    6. Chapter 74: Rate of pregnancy-related relapse in Multiple Sclerosis
  28. Section 10: Autoimmune Neurology
  29. Author: Christopher Doughty
  30. Senior Author: Nagagopal Venna
    1. Chapter 75: EULAR recommendations for treatment of primary CNS vasculitis
    2. Chapter 76: NMDA-ab receptor encephalitis with ovarian teratoma
    3. Chapter 77: Identification of Sjogren’s ganglionopathy
    4. Chapter 78: IVIG for stiff person syndrome
  31. Section 11: Epilepsy
  32. Author: Anna Bank
  33. Senior Author: Brandon Westover
    1. Chapter 79: Lorazepam for treatment of status epilepticus
    2. Chapter 80: Magnesium for prevention of eclampsia
    3. Chapter 81: Antiepileptic drug treatment after a first unprovoked seizure
    4. Chapter 82: Intravenous vs intramuscular benzodiazepines for status epilepticus
    5. Chapter 83: Continuous EEG monitoring for evaluation of nonconvulsive status epilepticus
  34. Section 12: Headache & Pain
  35. Author: Sheena Chew
  36. Senior Author: William Mullally
    1. Chapter 84: Sumatriptan for migraine
    2. Chapter 85: Topiramate for migraine prevention
    3. Chapter 86: Duloxetine for chemo-induced painful neuropathy
    4. Chapter 87: Pregabalin for neuropathic pain
    5. Chapter 88: Amitriptyline prophylaxis for headache
    6. Chapter 89: Divalproex for migraine prophylaxis
  37. Section 13: Cognitive Neurology
  38. Author: Emer McGrath
  39. Senior Author: Scott M. McGinnis
    1. Chapter 90: Donepezil for Alzheimer’s Disease
    2. Chapter 91: Memantine in addition to donepezil for Alzheimer’s disease
    3. Chapter 92: Rivastigmine for dementia with Lewy bodies
    4. Chapter 93: Melatonin for REM sleep behavior disorder
    5. Chapter 94: Agitation in dementia
  40. Section 14: Pediatric Neurology
  41. Author: Missy Walker
  42. Senior Author: Patricia Musolino
    1. Chapter 95: Treatment of infantile spasms
    2. Chapter 96: Pharmaco vs behavioral therapy for ADHD
    3. Chapter 97:: Ketogenic diet for treatment of childhood epilepsy
    4. Chapter 98: Hypothermia for neonates with hypoxic-ischemic encephalopathy
    5. Chapter 99: Febrile seizures
    6. Chapter 100: When to Stop Antiepileptic drugs in children with epilepsy
Editors Biography

Kate T Brizzi MD
Instructor of Neurology
Department of Neurology
Massachusetts General Hospital
Harvard Medical School
Boston, Massachusetts

Ayush Batra MD
Assistant Professor of Neurology
Ken & Ruth Davee Department of Neurology
Northwestern Memorial Hospital
Northwestern University Feinberg School of Medicine
Chicago, Illinois

Joel Salinas MD, MBA, MSc
Instructor of Neurology
Department of Neurology
Massachusetts General Hospital
Harvard Medical School
Boston, Massachusetts

Nancy Wang MD
Clinical Fellow
Pappas Center for Neuro-Oncology
Massachusetts General Hospital
Boston, Massachusetts

Emily L Aaronson MD
Chief Resident
Harvard Affiliated Emergency Medicine Residency
Massachusetts General Hospital
Brigham and Women’s Hospital
Boston, Massachusetts

Erik L Antonsen MD, PhD
Assistant Professor of Medicine
Section of Emergency Medicine
Assistant Professor of Space Medicine
Center for Space Medicine
Baylor College of Medicine
Attending Physician
Ben Taub General Hospital
Houston, Texas

Arjun K Venkatesh MD, MBA, MHS
Director, Quality and Safety Research and Strategy
Instructor, Department of Emergency Medicine
Scientist, Center for Outcomes
Research and Evaluation
Yale University School of Medicine
New Haven, Connecticut

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