Aerosols and the Human Lung: An Introduction | KitaabNow

Aerosols and the Human Lung: An Introduction

  • Authors: Chantal J Darquenne, Otmar Schmid, G Kim Prisk
  • ISBN: 9789811212178
  • Publisher: World Scientific Publishing
  • Edition: 1st
  • Publication Date: April 13, 2020
  • Format: Hardback – 224 pages
  • Language: English


This book provides a comprehensive overview of the field of aerosol science related to particle inhalation and its effect on the lung, predominately in humans. It covers the basics of aerosol behavior, transport, deposition, clearance, and effects of aerosols, both environmental and therapeutic. Aimed at the researcher entering the field of aerosol inhalation it provides a valuable introductory resource in an accessible format.


Researchers working in the multi-faceted field of aerosol science; those in the related fields of respiratory medicine and environmental health.

Table of Contents
  1. Introduction
  2. The Respiratory System
  3. Aerosol Transport and Deposition: The Basics
  4. Aerosol Measurement Techniques
  5. Determination of Aerosol Deposition
  6. Clearance of Deposited Particles
  7. Aerosols as a Diagnostic Tool
  8. Aerosol Therapeutics
  9. Ambient and Indoor Aerosol
  10. Adverse Health Effects of Aerosols
  11. Aerosols in Unusual Environments
  12. Regulation of Particle Exposure
Authors Biography

Chantal Darquenne is a Professor of Medicine at the University of California, San Diego (UCSD). She earned her PhD degree in Applied Sciences from the Université Libre de Bruxelles (Belgium). She completed a postdoctoral fellowship in the Division of Physiology at UCSD where she still holds her current position. Dr Darquenne studies the deposition and dispersion of inhaled aerosols to gain greater insight into the mechanisms involved in particle transport in the lung. Her major research contributions in the field include the study of aerosol inhalations in humans in altered gravity, the development of numerical models that simulate the transport and deposition of aerosols in the lung, the use of Magnetic Resonance Imaging to measure aerosol deposition in animal models, the effect of lung disease such as COPD on both regional and overall aerosol deposition, and the study of upper airway dynamics during breathing and its effect on aerosol transport. She is the President of the International Society for Aerosols in Medicine (2019–2021).

Otmar Schmid is head of the Pulmonary Aerosol Delivery Group at the Helmholtz Zentrum München and the Comprehensive Pneumology Center in Munich, Germany. He is also Adjunct Assistant Professor at the Missouri University of Science and Technology (MST), from which he hold a PhD degree in physics. He has more than 20 years of experience in aerosol science working in the fields of ambient aerosol characterization, combustion aerosols and particle lung deposition. More recently, his research focus has shifted to therapeutic aerosols, dosimetry and biokinetics of aerosols in the lungs and the biological effects of nanoparticles. He holds patents related to aerosol technology and he has worked intensely towards bridging the gap between aerosol science, medicine and toxicology. He has served on the boards of related professional societies including the Association for Aerosol Research (GAeF) and the International Society of Aerosols in Medicine (ISAM).

Kim Prisk earned his PhD from the University of Otago in 1983 and has been at the University of California, San Diego ever since. He worked extensively on studies of the human lung in weightlessness in spaceflight on both the Space Shuttle and on the International Space Station. These studies were extended to studies on aerosol transport and deposition and the influence of gravity on these processes using parabolic flight. More recently he has worked on the development and use of functional imaging techniques using MRI to quantitatively measure both ventilation and perfusion in the human lung. Despite the low signal to noise environment for MRI in the lung, the techniques offer imaging without the constraints of radiation dose or the use of injected contrast agents, making them well-suited for studies that require repeated imaging. He is an associate editor for the Journal of Applied Physiology with an emphasis on pulmonary gas exchange and environmental physiology.

Additional information
Weight0.467 kg

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