Biochemistry: Concepts and Connections (2nd Edition – Global)

Description

For courses in biochemistry.

Engage students in biochemistry visually and through real-world applications

Biochemistry: Concepts and Connections engages students with a unique approach to visualization, synthesis of complex topics, and connections to the real world. The author team builds quantitative reasoning skills and provides students with a rich, chemical perspective on biological processes. The text emphasizes fundamental concepts and connections, showing how biochemistry relates to practical applications in medicine, agricultural sciences, environmental sciences, and forensics.

The newly revised 2nd Edition integrates even more robust biochemistry-specific content in Mastering^™ Chemistry, creating an interactive experience for today’s students. New Threshold Concept Tutorials help students master the most challenging and critical ideas in biochemistry, while Interactive Case Studies connect course material to the real world by having students explore actual scientific data from primary literature.

Mastering Chemistry is not included. Students, if Mastering Chemistry is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN. Mastering Chemistry should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information.

Reach every student by pairing this text with Mastering Chemistry

Pearson Mastering Chemistry is the teaching and learning platform that empowers you to reach every student. By combining trusted author content with digital tools and a flexible platform, Pearson Mastering Chemistry personalizes the learning experience and improves results for each student.

Key Features

This title is a Pearson Global Edition. The Editorial team at Pearson has worked closely with educators around the world to include content which is especially relevant to students outside the United States.

• The groundbreaking visual narrative highlights and reinforces overarching themes (chemical logic, regulation, interface between chemistry and biology) using a wide range of graphic representations, from macromolecules to cellular structures as well as reaction mechanisms and metabolic pathways. Students see and grasp the bigger picture and further their understanding of the material including the mapping of bioenergetic calculations to three-dimensional structures, precise reference charts that highlight chemical interrelationships, integrated text explanations, and detailed molecular models.
• All art was created by medical illustrators and reviewed by a faculty advisory board made up of members of VIBE (Visualization in Biochemistry Education) Research Group to ensure that all visuals are beautifully accurate and pedagogically sound.
• Increased – Two New Foundation Figures bring the total in the text to 10. Foundation Figures integrate core chemical and biological connections visually, providing a way to organize highly complex and detailed material and making biochemistry more manageable, understandable, and easier to synthesize. Existing Foundation Figures were reviewed by a learning science team and honed to be more pedagogically effective. Foundation Figures include dedicated questions to be used in class via Learning Catalytics or can be assigned in Mastering as stepwise animations with follow-up assessment.
• Enhanced connection between complex multi-step art pieces and the related in-text discussion by adding color-coded step callouts (from the art) to the in-text discussion. This allows students to more easily connect the details in the text to the art.

Makes connections between biochemistry and the real world

• Expanded – Tools of Biochemistry highlight the most important research techniques and emphasize biochemistry as an experimental science by including 16 separate sections of cutting edge references. These end-of-chapter references (about twelve per chapter) include links to Nobel Prize lectures for example.
• Revised – Concept and Connection statements highlighted in the narrative call students’ attention to fundamental concepts as well as their real-world applications and demonstrate how individual topics are related.
• New – End-of-chapter problems bring the total per chapter to 15-25 and often include real-world applications.. Approximately half of the problems have brief answers at the end of the book, with complete answers provided in a separate solutions manual.

Written with today’s students in mind

• The concise presentation and organizational choices of the text result from the combined classroom experience of the renowned author team, providing students with a resource they will use during the course and a solid reference for their futures:
  • Each chapter builds upon student understanding of fundamentals, presenting  the theme of structure and function and covering only the content that students actually need.
  • The first several chapters introduce biochemistry as a quantitative science with Chapters 2 and 3 focusing on water, the matrix of life, and bioenergetics. Subsequent chapters present structure and function of biological molecules, followed by intermediary metabolism, and then genetic biochemistry.
  • The text presents the principles of biochemical techniques throughout as well as many, diverse real-world applications.

Mastering Chemistry is not included. Students, if Mastering Chemistry is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN. Mastering Chemistry should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information.

Visualization tools help students understand what’s happening on the cellular level and synthesize complex information

• Expanded – Foundation Figure Tutorials present two new figures. The figures walk students through two-page book spreads using stepwise animations to break them into tractable pieces. Follow-up questions assess student understanding on the important concepts the figures portray. These self-paced tutorials in the Pearson eText and Mastering Chemistry coach students with hints and feedback specific to their individual misconceptions.
• Dynamic Study Modules (DSMs) help students study effectively on their own by continuously assessing their activity and performance in real time. DSMs include General Chemistry as well as Biochemistry topics.
  • Students complete a set of questions and indicate their level of confidence in their answer.
  • Questions repeat until the student can answer them all correctly and confidently.
  • These are available as graded assignments prior to class and are accessible on smartphones, tablets, and computers.
• BioFlix® 3D movie-quality animations help your students visualize complex biochemistry topics and include automatically graded tutorial  activities.
• Students can explore interactive 3D molecular models and related follow-up questions provide answer-specific feedback.

Mastering Chemistry now boasts double the biochemistry-specific assets to help students connect course materials to real world applications

• New – Interactive Case Studies, assignable in Mastering Chemistry, put students into the role of a biochemist in real-world scenarios, immersing them in topics such as combating multidrug resistant bacteria using Michaelis-Menton enzyme kinetics. Each activity is designed to help students connect the course material to the real world by having them explore actual scientific data from primary literature. Students solve problems that matter to them using a myriad of question types such as multiple choice, drag and drop, and plotting results on graphs.
• Updated Biochemistry-Specific Tutorial Problems, featuring specific wrong-answer feedback, hints, and a wide variety of educationally effective content, guide your students through the most challenging topics.
  • The hallmark Hints and Feedback offer instruction similar to what students would experience in an office hour, allowing them to learn from their mistakes without being given the answer.
  • Extended coverage of biochemistry topics and new real-world applications such as non-glucose metabolism have been added to the 2nd Edition.
• Twice as many pre-lecture reading questions with links directly to the eText help your students come to class prepared to learn.
• 100 New End-of-Chapter Problems from the textbook are assignable within Mastering Chemistry and help students prepare for the types of questions that may appear on an exam. All end-of-chapter problems are automatically graded and include author-written solutions.

Students get the threshold concept coverage they need to succeed

• New – Threshold Concept Tutorials and in-class assessment questions for Learning Catalytics help students assess their understanding and master important threshold concepts that often act as barriers to learning the content in biochemistry courses. The topics were chosen based on recent research in the journal of Biochemistry and Molecular Biology Education.
• Learning Catalytics^™ helps generate class discussion, customize lectures, and promote peer-to-peer learning with real-time analytics. Learning Catalytics acts as a student response tool that uses students’ smartphones, tablets, or laptops to engage them in more interactive tasks and thinking.
  • New – Biochemistry-specific questions tied to threshold concepts
  • Upload a full PowerPoint^® deck to easily create slide questions
  • Help your students develop critical thinking skills
  • Monitor responses to find out where your students are struggling
  • Rely on real-time data to adjust your teaching strategy

Automatically group students for discussion, teamwork, and peer-to-peer learning

New to this Edition

A first-in-class art program visually engages students in biochemistry

• The groundbreaking visual narrative highlights and reinforces overarching themes (chemical logic, regulation, interface between chemistry and biology) using a wide range of graphic representations, from macromolecules to cellular structures as well as reaction mechanisms and metabolic pathways. Students see and grasp the bigger picture and further their understanding of the material including the mapping of bioenergetic calculations to three-dimensional structures, precise reference charts that highlight chemical interrelationships, integrated text explanations, and detailed molecular models.
• Increased – Two New Foundation Figures bring the total in the text to 10. Foundation Figures integrate core chemical and biological connections visually, providing a way to organize highly complex and detailed material and making biochemistry more manageable, understandable, and easier to synthesize. Existing Foundation Figures were reviewed by a learning science team and honed to be more pedagogically effective. Foundation Figures include dedicated questions to be used in class via Learning Catalytics or can be assigned in Mastering as stepwise animations with follow-up assessment.
• Enhanced connection between complex multi-step art pieces and the related in-text discussion by adding color-coded step callouts (from the art) to the in-text discussion. This allows students to more easily connect the details in the text to the art.

Makes connections between biochemistry and the real world

• Expanded – Tools of Biochemistry highlight the most important research techniques and emphasize biochemistry as an experimental science by including 16 separate sections of cutting edge references. These end-of-chapter references (about twelve per chapter) include links to Nobel Prize lectures for example.
• Revised – Concept and Connection statements highlighted in the narrative call students’ attention to fundamental concepts as well as their real-world applications and demonstrate how individual topics are related.
• End-of-chapter problems bring the total per chapter to 15-25 and often include real-world applications.. Approximately half of the problems have brief answers at the end of the book, with complete answers provided in a separate solutions manual.

Mastering Chemistry is not included. Students, if Mastering Chemistry is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN. Mastering Chemistry should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information.

Visualization tools help students understand what’s happening on the cellular level and synthesize complex information

• Expanded – Foundations Figure Tutorials present two new figures. The figures walk students through two-page book spreads using stepwise animations to break them into tractable pieces. Follow-up questions assess student understanding on the important concepts the figures portray. These self-paced tutorials in the Pearson eText and Mastering Chemistry coach students with hints and feedback specific to their individual misconceptions.

Mastering Chemistry now boasts double the biochemistry-specific assets to help students connect course materials to real world applications

• Interactive Case Studies, assignable in Mastering Chemistry, put students into the role of a biochemist in real-world scenarios, immersing them in topics such as combating multidrug resistant bacteria using Michaelis-Menton enzyme kinetics. Each activity is designed to help students connect the course material to the real world by having them explore actual scientific data from primary literature. Students solve problems that matter to them using a myriad of question types such as multiple choice, drag and drop, and plotting results on graphs.
• Updated Biochemistry-Specific Tutorial Problems, featuring specific wrong-answer feedback, hints, and a wide variety of educationally effective content, guide your students through the most challenging topics.
  • The hallmark Hints and Feedback offer instruction similar to what students would experience in an office hour, allowing them to learn from their mistakes without being given the answer.
  • Extended coverage of biochemistry topics and new real-world applications such as non-glucose metabolism have been added to the 2nd Edition.
• Twice as many pre-lecture reading questions with links directly to the eText help your students come to class prepared to learn.
• 100 New End-of-Chapter Problems from the textbook are assignable within Mastering Chemistry and help students prepare for the types of questions that may appear on an exam. All end-of-chapter problems are automatically graded and include author-written solutions.

Students get the threshold concept coverage they need to succeed

Threshold Concept Tutorials and in-class assessment questions for Learning Catalytics help students assess their understanding and master important threshold concepts that often act as barriers to learning the content in biochemistry courses. The topics were chosen based on recent research in the journal of Biochemistry and Molecular Biology Education

Table of Contents

1.  Biochemistry and the Language of Chemistry
2.  The Chemical Foundation of Life: Weak Interactions in an Aqueous Environment
3.  The Energetics of Life
4.  Nucleic Acids
5.  Introduction to Proteins: The Primary Level of Protein Structure
6.  The Three-Dimensional Structure of Proteins
7.  Protein Function and Evolution
8.  Enzymes: Biological Catalysts
9.  Carbohydrates: Sugars, Saccharides, Glycans
10.  Lipids, Membranes, and Cellular Transport
11.  Chemical Logic of Metabolism
12.  Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway
13.  The Citric Acid Cycle
14.  Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism
15.  Photosynthesis
16.  Lipid Metabolism
17.  Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates
18.  Amino Acid and Nitrogen Metabolism
19.  Nucleotide Metabolism
20.  Mechanisms of Signal Transduction
21.  Genes, Genomes, and Chromosomes
22.  DNA Replication
23.  DNA Repair, Recombination, and Rearrangement
24.  Transcription and Post-transcriptional Processing
25.  Information Decoding: Translation and Post-translational Protein Processing
26.  Regulation of Gene Expression
27. APPENDIX I: Answers to Selected Problems
28. APPENDIX ii: References
29. Glossary
30. Credits
31. Index