Goldfrank’s Toxicologic Emergencies (11th Edition)

Description

The best edition yet of the landmark text in medical toxicology

A Doody’s Core Title for 2019!

Covering every aspect of poison management, this indispensable case-based resource has been thoroughly refreshed to deliver evidence-based principles viewed through the lens of an active bedside clinical practice. In no other reference will you find such a diverse roster of esteemed editors and authors who deliver expert insights into every type of toxicologic emergency, whether due to substance abuse or exposure to toxins.

Fully referenced and supported by a cohesive organization and full-color format, Goldfrank’s begins with a historical perspective on medical toxicology principles and the general approach to the patient. It then progresses to the fundamental principles of medical toxicology, encompassing biochemical and molecular concepts; the effect of xenobiotics on vital organs and body systems; and toxicologic principles in special populations.

The Eleventh Edition of Goldfrank’s Toxicologic Emergencies is the most rigorous volume to date, driven by a precise analysis of the latest medical literature and complex cases designed to facilitate differential diagnosis.

New to this Edition

•  Additional cases and “Special Considerations” chapters designed to enhance clinical decision-making and patient outcomes
• New “Antidotes in Depth” provides timely, critical information on toxicologic treatment strategies
• New content on toxicogenomics explores its increasingly important role in predictive toxicology
• Chapter-ending bulleted summaries of key points
• Updated coverage of synthetics such as “K2”
• Revised chapters on medical, clinical, and chemical toxicology include updated insights on poison emergencies, treatment strategies, and risk assessment tools

Table of Contents

1. Historical Principles and Perspectives – Paul M. Wax
2. Toxicologic Misfortunes and Catastrophes in History – Paul M. Wax
3. PART A
   1. THE GENERAL APPROACH TO THE PATIENT
   2. Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes – Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Lewis R. Goldfrank and Robert S. Hoffman
   3. Principles of Managing the Acutely Poisoned or Overdosed Patient – Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Lewis R. Goldfrank and Robert S. Hoffman [include eCPR, critical care dispositions]
   4. SC1. Principles of Antidote Stocking
   5. Decontamination Principles: Prevention of Gastrointestinal Absorption – Lotte C. G. Hoegberg and Anne-Bolette Gude
   6. SC2. Decontamination Principles: Prevention of Dermal, Inhalational and Ocular Absorption
   7. A1. Activated Charcoal – Silas W. Smith and Mary Ann Howland
   8. A2. Whole-Bowel Irrigation and Other Intestinal Evacuants – Silas W. Smith and Mary Ann Howland
   9. Principles and Techniques Applied to Enhance Elimination – David S. Goldfarb and Marc Ghannoum
   10. Laboratory Principles – Petrie M. Rainey
   11. Principles of Diagnostic Imaging – David T. Schwartz
   12. Pharmacokinetic and Toxicokinetic Principles – Mary Ann Howland
4. PART B
   1. THE FUNDAMENTAL PRINCIPLES OF MEDICAL TOXICOLOGY
   2. SECTION I
      1. BIOCHEMICAL AND MOLECULAR CONCEPTS
      2. Chemical Principles – Stephen J. Traub and Lewis S. Nelson
      3. Biochemical and Metabolic Principles – Kurt C. Kleinschmidt and Kathleen A. Delaney
      4. Fluid, Electrolyte, and Acid–Base Principles – Alan N. Charney and Robert S. Hoffman
      5. Neurotransmitters and Neuromodulators – Steven C. Curry, Ayrn D. O’Connor, Kimberlie A. Graeme, Kirk C. Mills, and Aaron B. Skolnik
      6. Withdrawal Principles – Richard J. Hamilton and [new author]
   3. SECTION II
      1. PATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS
      2. Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles – Cathleen Clancy
      3. Cardiologic Principles II: Hemodynamics – [new author] and Robert A. Hessler
      4. Dermatologic Principles – Jesse M. Lewin, Neal A. Lewin, and Lewis S. Nelson
      5. SC3. Transdermal Toxicology – Lewis S. Nelson
      6. Gastrointestinal Principles – Matthew D. Zuckerman and Richard J. Church
      7. Genitourinary Principles – Jason Chu
      8. Hematologic Principles – Marco L.A. Sivilotti
      9. Hepatic Principles – Kathleen A. Delaney
      10. Neurologic Principles – Rama B. Rao
      11. Oncologic Principles – Richard Wang
      12. Ophthalmic Principles – Adhi Sharma
      13. Otolaryngologic Principles – [new author] and William Chiang
      14. Psychiatric Principles – Erin A. Zerbo and Andrea M. Kondracke