Medical Parasitology (5th Revised Edition)

Description

Focusing on current and future uses of microbes as production organisms, this practice-oriented textbook complements traditional texts on microbiology and biotechnology.
The editors have brought together leading researchers and professionals from the entire field of industrial microbiology and together they adopt a modern approach to a well-known subject. Following a brief introduction to the technology of microbial processes, the twelve most important application areas for microbial technology are described, from crude bulk chemicals to such highly refined biomolecules as enzymes and antibodies, to the use of microbes in the leaching of minerals and for the treatment of municipal and industrial waste. In line with their application-oriented topic, the authors focus on the “translation” of basic research into industrial processes and cite numerous successful examples. The result is a first-hand account of the state of the industry and the future potential for microbes in industrial processes.
Interested students of biotechnology, bioengineering, microbiology and related disciplines will find this a highly useful and much consulted companion, while instructors can use the case studies and examples to add value to their teaching.

Key Features

•  All chapters have been thoroughly revised, without making it bulky
• Classification of parasites and treatment of parasitic infections have been updated
• New Multiple Choice Questions (MCQs) have been added
• New parasitic figures have been added
• Clear, colored and uncomplicated diagrams are given throughout the text
• Pictures of gross and histopathological sections are also given
• Includes well-illustrated life cycles and pathologic lesions
• Chapter- overview of Parasitology at the end serves
• Ready reckoner to revise medical parasitology
• Basis to identify the weak topics in understanding the subject
• Diagrammatic representation of relative sizes and morphology of protozoa and helmentic eggs at the end provides good visual impact for subject understanding

Table of Contents

1. Preface
2. Historical Overview and Future Perspective
3. Use of Fermentation Procedures Before the Discovery of Microorganisms (Neolithic Era = New Stone Age Until 1850)
4. Investigation of Microorganisms and Beginning of Industrial Microbiology (1850 Until 1940)
5. Development of New Products and Procedures: Antibiotics and Other Biomolecules (From 1940)
6. Genetic Engineering Is Introduced into Industrial Microbiology (From Roughly 1980)
7. Future Perspectives: Synthetic Microbiology
8. References
9. Further Reading
10. Bioprocess Engineering
11. Introduction
12. Nonstructured Models
13. Oxygen Transport
14. Heat Generating Aerobic Processes
15. Product Recovery
16. Modeling and Simulation of Reactor Behavior
17. Scale‐up
18. References
19. Further Reading
20. Food
21. Fermented Foods
22. Microorganisms and Metabolism
23. Yeast Fermentations – Industrial Application of Saccharomyces Species
24. Vinegar – Incomplete Ethanol Oxidation by Acetic Acid Bacteria Such as Gluconobacter oxydans
25. Bacterial and Mixed Fermentations – Industrial Application of Lactic Acid Bacteria, With or Without Yeast or Molds
26. Fungi as Food
27. Conclusions and Outlook
28. References
29. Further Reading
30. Technical Alcohols and Ketones
31. Introduction
32. Ethanol Synthesis by Saccharomyces cerevisiae and Clostridium autoethanogenum
33. 1,3‐Propanediol Synthesis by Escherichia coli
34. Butanol and Isobutanol Synthesis by Clostridia and Yeast
35. Acetone Synthesis by Solventogenic Clostridia
36. Outlook
37. Further Reading
38. Organic Acids
39. Introduction
40. Citric Acid
41. Lactic Acid
42. Gluconic Acid
43. Succinic Acid
44. Itaconic Acid
45. Downstream Options for Organic Acids
46. Perspectives
47. Further Reading
48. Amino Acids
49. Introduction
50. Production of Amino Acids
51. L‐Glutamate Synthesis by Corynebacterium glutamicum
52. L‐Lysine
53. L‐Threonine Synthesis by Escherichia coli
54. L‐Phenylalanine
55. Outlook
56. Further Reading
57. Vitamins, Nucleotides, and Carotenoids
58. Application and Economic Impact
59. L‐Ascorbic Acid (Vitamin C)
60. Riboflavin (Vitamin B2)
61. Cobalamin (Vitamin B12)
62. Purine Nucleotides
63. β‐Carotene
64. Perspectives
65. Further Reading
66. 8 Antibiotics and Pharmacologically Active Compounds
67. Microbial Substances Active Against Infectious Disease Agents or Affecting Human Cells
68. β‐Lactams
69. Lipopeptides
70. Macrolides
71. Tetracyclines
72. Aminoglycosides
73. Claviceps Alkaloids
74. Perspectives
75. Further Reading
76. Pharmaceutical Proteins
77. History, Main Areas of Application, and Economic Importance
78. Industrial Expression Systems, Cultivation and Protein Isolation, and Legal Framework
79. Insulins
80. Somatropin
81. Interferons – Application and Manufacturing
82. Human Granulocyte Colony‐Stimulating Factor
83. Vaccines
84. Antibody Fragments
85. Enzymes
86. Peptides
87. View – Future Economic Importance
88. Further Reading
89. Enzymes
90. Fields of Application and Economic Impacts
91. Enzyme Discovery and Improvement
92. Production Process for Bacterial or Fungal Enzymes
93. Polysaccharide‐Hydrolyzing Enzymes
94. Enzymes Used as Cleaning Agents
95. Feed Supplements – Phytases
96. Enzymes for Chemical and Pharmaceutical Industry
97. Enzymes as Highly Selective Tools for Research and Diagnostics
98. Perspectives
99. References
100. Further Reading
101. Microbial Polysaccharides
102. Introduction
103. Heteropolysaccharides
104. Homopolysaccharides
105. Perspectives
106. Further Reading
107. Steroids
108. Fields of Applications and Economic Importance
109. Advantages of Biotransformations During Production of Steroids
110. Development of Production Strains and Production Processes
111. Applied Types of Biotransformation
112. Synthesis of Steroids in Organic – Aqueous Biphasic System
113. Side‐chain Degradation of Phytosterols by Mycobacterium to Gain Steroid Intermediates
114. Biotransformation of Cholesterol to Gain Key Steroid Intermediates
115. 11‐Hydroxylation by Fungi During Synthesis of Corticosteroids
116. Δ1‐Dehydrogenation by Arthrobacter for the Production of Prednisolone
117. 17‐Keto Reduction by Saccharomyces in Testosterone Production
118. Double‐Bond Isomerization of Steroids
119. Perspectives
120. References
121. Further Reading
122. Bioleaching
123. Acidophilic Microorganisms Dissolve Metals from Sulfide Ores
124. Bioleaching of Copper, Nickel, Zinc, and Cobalt
125. Gold
126. Uranium
127. Perspectives
128. References
129. Further Reading
130. Wastewater Treatment Processes
131. Introduction
132. Biological Basics of Carbon, Nitrogen, and Phosphorus Removal from Sewage
133. Wastewater Treatment Processes
134. Advanced Wastewater Treatment
135. Future Perspectives
136. References
137. Further Reading
138. Index
139. End User License Agreement