Medical Pharmacology and Therapeutics (5th Edition)

Description

Medical Pharmacology & Therapeutics, now in its fifth edition, offers medical students all they need to know to become safe and effective prescribers. It forms a complete, integrated resource for basic pharmaceutical science, pathophysiology, clinical pharmacology, and therapeutics.

Key Features

The fifth edition has been extensively revised and updated throughout. Key features include:

• Clear, disease-based approach.
• Presentation of how drugs are used in clinical practice.
• Succinct explanations of the major pathogenic mechanisms of each disease and consequent clinical signs and symptoms.
• Comprehensive reviews of major drug classes relevant to each disease.
• Structured approach to the principles of disease management – outlining core principles of drug choice and planning a therapeutic regimen for common diseases.
• Quick-reference drug compendia illustrating key similarities and differences among all BNF-listed drugs in each class.
• Comes with free e-book on StudentConsult.
• New sections on key and evolving topics, including prescribing safety and pharmacovigilance.
• Updated figures to further clarify complex areas.
• Over 800 revised multiple-choice and case-based questions for self-assessment.

Table of Contents

1. SECTION 1 General principles
   1. Principles of pharmacology and mechanisms of drug action
   2. Pharmacokinetics
   3. Drug discovery, safety and efficacy
   4. The nervous system, neurotransmission and the peripheral autonomic nervous system
2. SECTION 2 The cardiovascular system
   1. Ischaemic heart disease
   2. Systemic and pulmonary hypertension
   3. Heart failure
   4. Cardiac arrhythmias
   5. Cerebrovascular disease and dementia
   6. Peripheral vascular disease
   7. Haemostasis
3. SECTION 3 The respiratory system
   1. Asthma and chronic obstructive pulmonary disease
   2. Respiratory disorders: cough, respiratory stimulants, cystic fibrosis and neonatal respiratory distress syndrome
4. SECTION 4 The renal system
   1. Diuretics
   2. Disorders of micturition
   3. Erectile dysfunction
5. SECTION 5 The nervous system
   1. General anaesthetics
   2. Local anaesthetics
   3. Opioid analgesics and the management of pain
   4. Anxiolytics, sedatives and hypnotics
   5. The major psychotic disorders: schizophrenia and mania
   6. Depression, attention deficit hyperactivity disorder and narcolepsy
   7. Epilepsy
   8. Extrapyramidal movement disorders and spasticity
   9. Other neurological disorders: multiple sclerosis, motor neuron disease and Guillain-Barre syndrome
   10. Migraine
6. SECTION 6 The musculoskeletal system
   1. The neuromuscular junction and neuromuscular blockade
   2. Myasthenia gravis
   3. Non-steroidal anti-inflammatory drugs
   4. Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis
   5. Hyperuricaemia and gout
7. SECTION 7 The gastrointestinal system
   1. Nausea and vomiting
   2. Dyspepsia and peptic ulcer disease
   3. Inflammatory bowel disease
   4. Constipation, diarrhoea and irritable bowel syndrome
   5. Liver disease
   6. Obesity
8. SECTION 8 The immune system
   1. The immune response and immunosuppressant drugs
   2. Antihistamines and allergic disease
9. SECTION 9 The endocrine system and metabolism
   1. Diabetes mellitus
   2. The thyroid and control of metabolic rate
   3. Calcium metabolism and metabolic bone disease
   4. Pituitary and hypothalamic hormones
   5. Corticosteroids (glucocorticoids and mineralocorticoids)
   6. Female reproduction
   7. Androgens and anabolic steroids
   8. Anaemia and haematopoietic colony-stimulating factors
   9. Lipid disorders
10. SECTION 10 The skin and eyes
    1. Skin disorders
    2. The eye
11. SECTION 11 Chemotherapy
    1. Chemotherapy of infections
    2. Chemotherapy of malignancy
12. SECTION 12 General features: toxicity and prescribing
    1. Drug toxicity and overdose
    2. Substance abuse and dependence
    3. Prescribing, adherence and information about medicines
    4. Drug therapy in special situations
    5. Index

Authors Biography

Derek G. Waller
Consultant Cardiovascular Physician, University Hospital Southampton, Senior Clinical Lecturer, University of Southampton, Southampton, United Kingdom, Senior Medical Adviser to the British National Formulary

Anthony P. Sampson
Associate Professor in Clinical Pharmacology, Faculty of Medicine, University of Southampton, Southampton, United Kingdom