The Lung: Developmental Morphogenesis, Mechanobiology, and Stem Cells | KitaabNow

The Lung: Developmental Morphogenesis, Mechanobiology, and Stem Cells

  • Authors: Ahmed El-Hashash, Eiman Abdel Meguid
  • ISBN: 9789813277069
  • Publisher: World Scientific Publishing
  • Edition: 1st
  • Publication Date: March 29, 2019
  • Format: Hardback – 204 pages
  • Language: English


With detailed scientific background and up-to-date research, this book examines recent developmental and cell biology, mechanobiology and stem cell biology discoveries to help provide a better understanding of lung development, repair and regeneration. Lung regeneration is an urgent therapeutic priority. The current major challenge is the generation of complex vascularized structures that can ultimately support or replace impaired lung function. Recent discoveries in biomedical engineering are analysed within the structural context of the lung to help provide a better understanding of the innovative solutions that could be used for restoring normal morphogenesis and regeneration of the lung.

This also includes insights from basic developmental mechanisms of human lung development through the derivation and identification of stem cells, both from the early embryo as well as from differentiated organs and tissues. Suitable for a wide range of readers, including physicians and surgeons, scientists and researchers, and undergraduate and postgraduate students, this guide is an essential read for those working in the field of lung disease and development.


Developmental biologists, stem cell scientists, educated laypeople, science students at high school, undergraduate, graduate level, physicians and surgeons.

Table of Contents
  • Lung Pattern Formation and Development
  • Advances in Lung Developmental Mechanobiology
  • Pulmonary Complications Associated with Preterm Birth
  • Lung Stem and Progenitor Cells
  • Pattern Formation of the Anterior Endoderm and Developing Lung
  • Lung Cell Polarity, Fate and Mode of Division
  • General Summary, Concluding Remarks and Future Directions
Authors Biography

Ahmed El-Hashash has completed his PhD from Manchester University, UK. He is a fellow of the California Institute of Regenerative Medicine (CIRM) and New York University Medical School (MSSM), USA. Professor Ahmed El-Hashash worked as a Senior Biomedical Research Scientist at the Mount Sinai School of Medicine of New York University and Children’s Hospital Los Angeles. He was an Assistant Professor and the Principal Investigator of Stem Cell and Regenerative Medicine at the Keck School of Medicine and Ostrow School of Dentistry of The University of Southern California, USA. He has joined the University of Edinburgh, Edinburgh–Zhejiang International Campus, (ZJU) as the Tenure Track Associate Professor and Senior Principal Investigator of Biomedicine, Stem Cell and Regenerative Medicine. He is also the Adjunct Professor at the School of Basic Medical Science and School of Medicine, Zhejiang University. Hashash has several breakthrough discoveries in genes/enzymes that control stem cell behavior and regenerative medicine. He has published more than 34 papers and abstracts in reputed international journals and is serving as an editorial board member of repute. Professor El-Hashash acts as a discussion leader at the prestigious Gordon Research Seminar/Conference in USA, and a Peer Reviewer/International Extramural Review for The Medical Research Council (MRC) grant applications, London, UK. He has been invited to speak at several international conferences in USA, Spain, Greece, Egypt, and China. He is the editor or author of several books on stem cell and regenerative medicine.

Eiman Abdel Meguid, MBChB, PhD, P.G.C.H.E.T, F.H.E.A., is a Senior Lecturer at the Centre for Biomedical Sciences Education, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, UK. Dr Abdel Meguid obtained her bachelor degree in Medicine and Surgery and her PhD in Anatomy and Embryology from Alexandria University. She completed her PhD thesis at Eberhard-Karls Universität Tübingen, Germany. Dr Abdel Meguid is an innovative educator and researcher. She has published multiple scientific works in leading journals, and she is a reviewer and a member of the editorial board of a number of journals. She taught gross anatomy to medical, dental, human biology students and students enrolled in MSc in clinical anatomy. Her research interests are in the areas of stem cells, lung development, anatomical pedagogy, teaching strategies, and the inte-gration of novel technologies to enhance learning. She is a member of the Risk Management Group Committee and member of the Court of Examiners for the Royal College of Physicians and Surgeons, Glasgow. She is also a member of the Career Development Committee of the American Association of Clinical Anatomists.


Additional information
Weight 0.444 kg

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